Bacteria and viruses generally bring unpleasant thoughts to mind: having the flu, maybe, or food poisoning. However, these little guys have a positive place in our lives, like the microbes in our gut that keep us healthy. Amazingly, they may also hold the key to the future of cancer therapy. While scientists generally study human diseases in mice, rats, or even monkeys, nature’s tiniest beings have special properties we can learn from and harness for cancer treatment. Let’s go on a journey through three such examples – showing that when it comes to biological capability, size doesn’t matter.
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The history of science is full of examples of discovery, both intentional and accidental. But how do scientists study subject matter incapable of being explained by simple models? And additionally, if science can produce favorable results (say, in the clinic), to what extent does it matter whether or not the results can be fully explained? Here, Siddhant Iyer outlines the ways in which scientists may study as-of-yet unexplained phenomena and argues for a framework involving the use of complex models while also acknowledging limitations.