As it turns out, bears are capable of uniquely regulating a protein called PTEN (phosphatase and tensin homolog), which has a role in shutting off insulin signaling (among other things). So all we have to do is turn off PTEN in people and their type 2 diabetes will go away, right? Unfortunately, it’s not quite that simple.
Read More
The history of science is full of examples of discovery, both intentional and accidental. But how do scientists study subject matter incapable of being explained by simple models? And additionally, if science can produce favorable results (say, in the clinic), to what extent does it matter whether or not the results can be fully explained? Here, Siddhant Iyer outlines the ways in which scientists may study as-of-yet unexplained phenomena and argues for a framework involving the use of complex models while also acknowledging limitations.